Leitung der Teilprojekte

A10: Conformational switching induced by protein-ligand assembly

+2021

Prof. Dr. Iris Antes
Department für biowissenschaftliche Grundlagen
Wissenschaftszentrum Weihenstephan
Emil-Erlenmeyer-Forum 8
85354 Freising

AP06: The 26 S Proteasome: dynamics of the regulatory particle (2012-2020: A01)

Prof. Dr. Wolfgang Baumeister
Abteilung Molekulare Strukturbiologie
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

A03: Conformational regulation of the Hsp90 machinery
A06: Conformational plasticity of small Hsps

Z1: Biophysical methods
Z2: Central Tasks

Prof. Dr. Johannes Buchner
Lehrstuhl Biotechnologie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

A07: Regulation of the DEAD-box RNA helicase Sub2 by TREX

Prof. Dr. Elena Conti
Abteilung Zelluläre Strukturbiologie
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

AP09: Single-molecule studies of conformational switching and activation of the sodium-coupled symporter BetP

Prof. Dr. Thorben Cordes
Biozentrum der LMU München
Department Biologie I, Physikalische und Synthetische Biologie
Großhaderner Str. 2 - 4
82152 Martinsried
Email

expired: B04 - Regulation mechanisms and dynamic properties of mycobacterial protein kinase G

Dr. Sonja A. Dames
Biomolekulare NMR Spektroskopie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

B11: Structural mechanisms and cellular regulation of assembly-induced protein folding

Prof. Dr. Matthias Feige
Zelluläre Proteinbiochemie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

A02: Positioning, association and maturation of subunits during 20S proteasome assembly in pro- and eukaryotes

Prof. Dr. Michael Groll
Lehrstuhl Biochemie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

B13: Conformational switching of Bcl2 proteins and their complexes in a native membrane environment

Prof. Dr. Franz Hagn
Strukturelle Membranbiochemie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

A12: Mechanisms of chaperone-mediated protein folding and assembly

(2012-2016) AP01: Conformational changes during chaperonin-assisted protein folding

Prof. Dr. F. Ulrich Hartl
Abteilung Zelluläre Biochemie
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

A06: Conformational plasticity of small Hsps

AP02 = (2012-2016) B08: Alternative Splicing – switching and conformational diversity

Dr. Martin Haslbeck
Lehrstuhl Biotechnologie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

A12: Mechanisms of chaperone-mediated protein folding and assembly

Dr. Manajit Hayer-Hartl
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

B05: Structural dynamics of small GTPases under the influence of posttranslational modifications

Prof. Dr. Aymelt Itzen
Institut für Biochemie und Signaltransduktion
Zentrum für Experimentelle Medizin
Universitätsklinikum Hamburg-Eppendorf
Martinistrasse 52
20246 Hamburg
Email

AP08: Multi-scale molecular simulations and artificial design of long-range conformational switches (2016-2020: B12)

Prof. Dr. Ville R. I. Kaila
Department of Biochemistry and Biophysics (DBB)
Stockholm University
Svante Arrhenius väg 16C
10691 Stockholm, Sweden
Email

B06: Exploiting cross-amyloid interfaces to design peptides as modulators of amyloid self-assembly

Prof. Dr. Aphrodite Kapurniotu
Fachgebiet Peptidbiochemie
Wissenschaftszentrum Weihenstephan
Emil-Erlenmeyer-Forum 5
85354 Freising
Email

A11: Single molecule fluorescence methods for investigating conformational dynamics and allosteric effects in chaperones

Prof. Dr. Don C. Lamb
Fluorescence application in Biology
Department Chemie
Butenandtstrasse 11
81377 München
Email

expired: B10 - Genetic code expansion tools to study and control conformational dynamics and protein assembly

Prof. Dr. Kathrin Lang
Chemische Biologie
Departement Chemie und Angewandte Biowissenschaften
Eidgenössische Technische Hochschule Zürich
Vladimir-​Prelog-Weg 1-5/10
CH 8093  Zürich
Email

expired: B09 - Design of alternative protein conformations

Dr. Oliver Fritz Lange
Emmy-Noether Group
"Dynamics in biomolecular signal propagation"
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

B14: Translational control of protein folding by elongation kinetics

(2017-2020) AP03: Translational control of protein folding by ribosome transit kinetics

Prof. Dr. Danny Nedialkova
Biochemistry of Gene Expression
Department Chemie
Lichtenbergstrasse 4
85747 Garching
und
Abteilung Mechanismen der Proteinbiogenese
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

B07: Structural analysis of inhibitor-amyloid co-aggregates

Prof. Dr. Bernd Reif
Fachgebiet Festkörper-NMR-Spektroskopie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

A05: Mechanical control of protein conformations

Prof. Dr. Matthias Rief
Lehrstuhl Biophysik (E22)
Physik-Department
James-Franck Str. 1
85748 Garching
Email

AP06: The 26 S Proteasome: dynamics of the regulatory particle (2016-2020: A01)

Dr. Eri Sakata
Universitätsmedizin Göttingen
Institut für Auditorische Neurowissenschaften
Structural biology of protein quality control
Justus-von-Liebig-Weg 11
37077 Göttingen

ehemals:Max-Planck-Institut für Biochemie
Email

A03: Conformational regulation of the Hsp90 machinery
B03: Conformational control of multi-domain RNA binding proteins
Z1: Biophysical methods

Prof. Dr. Michael Sattler
Biomolekulare NMR-Spektroskopie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

B15: Conformational switches in viral regulatory proteins (2018-2020: AP05)

Prof. Dr. Anne Schütz
Department Chemie
Butenandtstr. 5-13
81377 München
Email

A13: Conformational switching during the production of branched polyubiquitin chains

(2017-2020) AP04: Conformational changes during ubiquitin and ubiquitin-like protein conjugation

Prof. Dr. Brenda A. Schulman
Abteilung Molekulare Maschinen und Signalwege
Max-Planck-Institut für Biochemie
Am Klopferspitz 18
82152 Martinsried
Email

AP07: Chaperones and TPR proteins in organellar protein import and chloroplast biogenesis (2016-2020: A04)

Dr. Serena Schwenkert
Biozentrum der LMU München
Department Biologie I, Botanik
Großhaderner Str. 2 - 4
82152 Martinsried
Email

A09: Small molecule induced conformational control of protein function and activity

Prof. Dr. Stephan A. Sieber
Organische Chemie II
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

AP07: HSP90 function in preprotein import into organelles (2012-2016: A04)

Prof. Dr. Jürgen Soll
Biozentrum der LMU München
Department Biologie I, Botanik
Großhaderner Str. 2 - 4
82152 Martinsried
Email

B02: Association-induced conformational switching in biomolecules studied by Molecular Dynamics simulations

Prof. Dr. Martin Zacharias
Lehrstuhl für Theoretische Biophysik (T38) - Molekulardynamik
Physik-Department
James-Franck Str. 1
85748 Garching
Email

A14: Engineering conformational dynamics of a de novo designed two-domain metalloenzyme

Prof. Dr. Cathleen Zeymer
Proteinchemie
Department Chemie
Lichtenbergstrasse 4
85747 Garching
Email

AP02 = (2012 - 2016) B08: Alternative Splicing – switching and conformational diversity

Prof. Dr. Ralf Zimmer
Lehr- und Forschungseinheit Bioinformatik
Department Informatik
Amalienstr. 17
80333 München
Email