Publikationen des SFB1035 von 2021
A03: Client binding shifts the populations of dynamic Hsp90 conformations through an allosteric network.
López Abraham, Dahiya Vinay, Delhommel Florent, Freiburger Lee, Stehle Ralf, Asami Sam, Rutz Daniel, Blair Laura, Buchner Johannes, Sattler Michael
Sci Adv. 2021 Dec 17
doi: 10.1126/sciadv.abl7295
B02: Binding induced functional domain motions in the argonaute characterized by adaptive advanced sampling.
Pourjafar-Dehkordi Danial, Zacharias Martin
PLoS Comput Biol. 2021 Nov 29
doi: 10.1371/journal.pcbi.1009625
A04: The TPR and J-domain containing proteins DJC31 and DJC62 are involved in abiotic stress response in Arabidopsis thaliana.
Dittmer Sophie, Kleine Tatjana, Schwenkert Serena
J Cell Sci. 2021 Sep 13
doi: 10.1242/jcs.259032
A11: Comparative analysis of the coordinated motion of Hsp70s from different organelles observed by single-molecule three-color FRET.
Voith von Voithenberg Lena, Barth Anders, Trauschke Vanessa, Demarco Benjamin, Tyagi Swati, Koehler Christine, Lemke Edward A., Lamb Don C.
Proc Natl Acad Sci USA. 2021 Aug 17
doi: 10.1073/pnas.2025578118
B11: IL-30 † (IL-27A): a familiar stranger in immunity, inflammation, and cancer.
Min Booki, Kim Dongkyun, Feige Matthias J.
Exp Mol Med. 2021 May 28
doi: 10.1038/s12276-021-00630-x
B10: Bioorthogonal chemistry.
Scinto Samuel L., Bilodeau Didier A., Hincapie Robert, Lee Wankyu, Nguyen Sean S., Xu Minghao, am Ende Christopher W., Finn M. G., Lang Kathrin, Lin Qing, Pezacki John Paul, Prescher Jennifer A., Robillard Marc S., Fox Joseph M.
Nat Rev Methods Primers. 2021 Apr 15
doi: 10.1038/s43586-021-00028-z
A11: FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices.
Lerner Eitan, Barth Anders, Hendrix Jelle, Ambrose Benjamin, Birkedal Victoria, Blanchard Scott C., Börner Richard, Sung Chung Hoi, Cordes Thorben., Craggs Timothy D., Deniz Ashok A., Diao Jiajie, Fei Jingyi, Gonzalez Ruben L., Gopich Irina V., Ha Taekjip, Hanke Christian A., Haran Gilad, Hatzakis Nikos S., Hohng Sungchul, Hong Seok-Cheol, Hugel Thorsten, Ingargiola Antonino, Joo Chirlmin, Kapanidis Achillefs N., Kim Harold D., Laurence Ted, Lee Nam Ki, Lee Tae-Hee, Lemke Edward A., Margeat Emmanuel, Michaelis Jens, Michalet Xavier, Myong Sua, Nettels Daniel, Peulen Thomas-Otavio, Plötz Evelyn, Razvag Yair, Robb Nicole C., Schuler Benjamin, Soleimaninejad Hamid, Tang Chun, Vafabakhsh Reza, Lamb Don C., Am Seidel Claus, Weiss Shimon
Elife. 2021 Mar 29
doi: 10.7554/eLife.60416
A03: The charged linker modulates the conformations and molecular interactions of Hsp90.
López Abraham, Elimelech Annika R., Klimm Karolin, Sattler Michael
Chembiochem. 2021 Mar 16
doi: 10.1002/cbic.202000699
B10: Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
Tremel Shirley, Ohashi Yohei, Morado Dustin R., Bertram Jessie, Perisic Olga, Brandt Laura T. L., von Wrisberg Marie-Kristin, Chen Zhuo A., Maslen Sarah L., Kovtun Oleksiy, Skehel Mark, Rappsilber Juri, Lang Kathrin, Munro Sean, Briggs John A. G., Williams Roger L.
Nat Commun. 2021 Mar 10
doi: 10.1038/s41467-021-21695-2
A13/Z1: Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler.
Liwocha Joanna, Krist David T., van der Heden van Noort Gerbrand J., Hansen Fynn M., Truong Vinh H., Karayel Ozge, Purser Nicholas, Houston Daniel, Burton Nicole, Bostock Mark J., Sattler Michael, Mann Matthias, Harrison Joseph S., Kleiger Gary, Ovaa Huib , Schulman Brenda A.
Nat Chem Biol. 2021 Mar
doi: 10.1038/s41589-020-00696-0
B11: Quality control of mislocalized and orphan proteins.
Kong Ka-Yiu Edwin, Coelho João P. L. , Feige Matthias J., Khmelinskii Anton
Exp Cell Res. 2021 Apr 28
doi: 10.1016/j.yexcr.2021.112617
A03: Structural elements in the flexible tail of the co-chaperone p23 coordinate client binding and progression of the Hsp90 chaperone cycle.
Biebl Maximilian M., López Abraham, Rehn Alexandra, Freiburger Lee, Lawatscheck Jannis, Blank Birgit, Sattler Michael, Buchner Johannes
Nat Commun. 2021 Feb 5
doi: 10.1038/s41467-021-21063-0
A06: Imbalances in the eye lens proteome are linked to cataract formation.
Schmid Philipp W. N., Lim Nicole C. H., Peters Carsten, Back Katrin C., Bourgeois Benjamin, Pirolt Franz, Richter Bettina, Peschek Jirka, Puk Oliver, Amarie Oana V., Dalke Claudia, Haslbeck Martin, Weinkauf Sevil, Madl Tobias, Graw Jochen, Buchner Johannes
Nat Struct Mol Biol. 2021 Feb
doi: 10.1038/s41594-020-00543-9
B05/B10: Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1.
Du Jiqing, von Wrisberg Marie-Kristin, Gülen Burak, Stahl Matthias, Pett Christian, Hedberg Christian, Lang Kathrin, Schneider Sabine, Itzen Aymelt
Nat Commun. 2021 Jan 19
doi: 10.1038/s41467-020-20702-2
B02: Targeting telomeres: Molecular Dynamics and free energy simulation of gold-carbene binding to DNA.
Nayis Asmar, Liebl Korbinian, Frost Christina V., Zacharias Martin
Biophys J. 2021 Jan 5
doi: 10.1016/j.bpj.2020.11.2263