Publikationen des SFB1035 von 2020

B05/B02/B03/A11: Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation.
^{Savitskiy Sergey, Wachtel Rudolf, Pourjafar-Dehkordi Danial, Kang Hyun-Seo, Trauschke Vanessa, Lamb Don C., Sattler Michael, Zacharias Martin, Itzen Aymelt}
iScience. 2020 Dec 15
doi: 10.1016/j.isci.2020.101940

 

B10: Increasing the chemical space of proteins in living cells via genetic code expansion.
^{Krauskopf Kristina, Lang Kathrin}
Curr Opin Chem Biol. 2020 Oct
doi: 10.1016/j.cbpa.2020.07.012
 

B11: Influence of glycosylation on IL-12 family cytokine biogenesis and function.
^{Bohnacker Sina, Hildenbrand Karen, Aschenbrenner Isabel, Müller Stephanie I., Esser-von Bieren Julia, Feige Matthias J.}
J Mol Immunol 2020 Oct
doi: 10.1016/j.molimm.2020.07.015
 

A12: Recent advances in understanding catalysis of protein folding by molecular chaperones.
^{Balchin David, Hayer-Hartl Manajit, Hartl F. Ulrich}  
FEBS Lett. 2020 Sep
doi: 10.1002/1873-3468.13844

 

A03: Hsp90 co-chaperones form plastic genetic networks apted to client maturation.
^{Biebl Maximilian M., Riedl Maximilian, Buchner Johannes}
Cell Rep. 2020 Aug 25
doi: 10.1016/j.celrep.2020.108063
 

A02/B12: Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis.
^{Bräuer Alois, Zhou Qiuqin, Grammbitter Gina L. C., Schmalhofer Maximilian, Rühl Michael, Kaila Ville R. I., Bode Helge B., Groll Michael}
Nat Chem. 2020 Aug
doi: 10.1038/s41557-020-0491-7

A06: Proteinaceous transformers: Structural and functional variability of human sHsps.
^{Riedl Mareike, Strauch Annika, Catici Dragana A. M., Haslbeck Martin}
Int J Mol Sci. 2020 Jul 30
doi: 10.3390/ijms21155448
 

B06: The human host-defense peptide cathelicidin LL-37 is a nanomolar inhibitor of amyloid self-assembly of islet amyloid polypeptide (IAPP).
^{Armiento Valentina, Hille Kathleen, Naltsas Denise, Lin Jennifer S., Barron Annelise E., Kapurniotu Aphrodite}
Angew Chem Int Ed Engl. 2020 Jul 27
doi: 10.1002/anie.202000148
 

A11/Z1: Determining the stoichiometry of small protein oligomers using steady-state fluorescence anisotropy.
^{Heckmeier Philipp J., Agam Ganesh, Teese Mark G., Hoyer Maria, Stehle Ralf, Lamb Don C., Langosch Diete}r
Biophys J. 2020 Jul 7
doi: 10.1016/j.bpj.2020.05.025
 

B05: Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.
^{Gülen Burak, Rosselin Marie, Fauser Joel, Albers Michael F. , Pett Christian, Krisp Christoph, Pogenberg Vivian, Schlüter Hartmut, Hedberg Christian, Itzen Aymelt}
Nat Chem. 2020 Jul 6
doi: 10.1038/s41557-020-0484-6
 

B05/A02: Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination.
^{Ernst Stefan, Ecker Felix, Kaspers Marietta S., Ochtrop Philipp, Hedberg Christian, Groll Michael, Itzen Aymelt}
Sci Adv. 2020 May 15
doi: 10.1126/sciadv.aaz8041
 

A11: QuanTI-FRET: a framework for quantitative FRET measurements in living cells.
^{Coullomb Alexis, Bidan Cécile M., Qian Chen, Wehnekamp Fabian, Oddou Christiane, Albigès-Rizo Corinne, Lamb Don C., Dupont Aurélie}
Sci Rep. 2020 Apr 16
doi: 10.1038/s41598-020-62924-w
 

B03: An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
^{Kang Hyun-Seo, Sánchez-Rico Carolina, Ebersberger Stefanie, Sutandy F. X. Reymond, Busch Anke, Welte Thomas, Stehle Ralf, Hipp Clara, Schulz Laura, Buchbender Andreas, Zarnack Kathi, König Julian, Sattler Michael}
Proc Natl Acad Sci USA. 2020 Mar 31
doi: 10.1073/pnas.1913483117

 

A12: Efficient catalysis of protein folding by GroEL/ES of the obligate chaperonin substrate MetF.
^{Singh Amit K, Balchin David,Imamoglu Rahmi, Hayer-Hartl Manajit, Hartl F. Ulrich}
J Mol Biol. 2020 Mar 27
doi: 10.1016/j.jmb.2020.02.031

 

B05/A02/B03: PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72.
^{Vieweg Sophie, Mulholland Katie, Bräuning Bastian, Kachariya Nitin, Lai Yu-Chiang,  Toth Rachel, Singh Pawan K., Volpi Ilaria, Sattler Michael, Groll Michael, Itzen Aymelt, Muq Miratul M. K.}
Biochem J. 2020 Mar 30
doi: 10.1042/BCJ20190664
 

B12/A03/Z1: Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90
^{Mader Sophie L., Lopez Abraham, Lawatscheck Jannis, Luo Qi, Rutz Daniel A., Gamiz-Hernandez Ana P., Sattler Michael, Buchner Johannes, Kaila Ville R. I.}
Nat Commun. 2020 Mar 16
doi: 10.1038/s41467-020-15050-0
 

A03/B12/B10: A methylated lysine is a switch point for conformational communication in the chaperone Hsp90
^{Rehn Alexandra, Lawatscheck Jannis, Jokisch Marie-Lena, Mader Sophie L., Luo Qi, Tippel Franziska, Blank Birgit , Richter Klaus, Lang Kathrin, Kaila Ville R.I. , Buchner Johannes}
Nat Commun. 2020 Mar 5
doi: 10.1038/s41467-020-15048-8
 

B05/B03: Conformational control of small GTPases by AMPylation.
^{Barthelmes Katja, Ramcke Evelyn, Kang Hyun-Seo, Sattler Michael, Itzen Aymelt}
Proc Natl Acad Sci USA. 2020 Mar 2
doi: 10.1073/pnas.1917549117
 

B06: Peptide-based molecular strategies to interfere with protein misfolding, aggregation, and cell degeneration.
^{Armiento Valentina, Spanopoulou Anna, Kapurniotu Aphrodite}
Angew Chem Int Ed Engl. 2020 Feb 24
doi: 10.1002/anie.201906908

B11/B10: Site-specific protein labeling with fluorophores as a tool to monitor protein turnover.
^{Mideksa Yonatan, Fottner Maximilian, Braus Sebastian, Weiß Caroline, Nguyen Tuan-Anh, Meier Susanne, Lang Kathrin, Feige Matthias J.}
Chembiochem. 2020 Feb 3
doi: 10.1002/cbic.201900651

B06: The human cathelicidin LL-37 is a nanomolar inhibitor of amyloid self-assembly of islet amyloid polypeptide (IAPP).
^{Armiento Valentina, Hille Kathleen, Naltsas Denise, Lin Jennifer S., Barron Annelise E., Kapurniotu Aphrodite}
Angew Chem Int Ed Engl. 2020 Jan 30
doi: 10.1002/anie.202000148
 

A12: Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein.
^{Imamoglu Rahmi, Balchin David, Hayer-Hartl Manajit, Hartl F. Ulrich}
Nat Commun. 2020 Jan 17
doi: 10.1038/s41467-019-14245-4

 

A09/A10: Acyldepsipeptide probes facilitate specific detection of caseinolytic protease P independent of its oligomeric and activity state.
^{Eyermann Barbara, Meixner Maximilian, Brötz-Oesterhelt Heike, Antes Iris, Sieber Stephan A.}
Chembiochem. 2020 Jan 15
doi: 10.1002/cbic.201900477
 

B13/A06: Quantifying the insertion of membrane proteins into lipid bilayer nanodiscs using a fusion protein strategy.
^{Häusler Elisabeth Fredriksson Kai, Goba Inguna, Peters Carsten, Raltchev Kolio, Sperl Laura, Steiner Andrea, Weinkauf Sevil, Hagn Franz}
Biochim Biophys Acta Biomembr. 2020 Jan 11
doi: 10.1016/j.bbamem.2020.183190
 

A06: Regulation of small heat-shock proteins by hetero-oligomer formation.
^{Mymrikov Evgeny V., Riedl Mareike, Peters Carsten, Weinkauf Sevil, Haslbeck Martin, Buchner Johannes}
J Biol Chem. 2020 Jan 3
doi: 10.1074/jbc.RA119.011143

A04: The ER luminal C-terminus of AtSec62 is critical for male fertility and plant growth in Arabidopsis thaliana.
^{Mitterreiter Melanie Jasmine, Bosch Franziska Annamaria, Brylok Thomas, Schwenkert Serena}
Plant J. 2020 Jan
doi: 10.1111/tpj.14483